What lies behind Scientific misconduct?

Recently many cases of scientific misconducts have been reported. Few years ago, a German Physicist at Bell Labs was found to fabricate data on his papers. Presently, starting from stem-cell Scientist of South Korea to several others in the United States. Most recently a Geneticist at the University of Wiscosin-Madison was under investigation for misconducts in some high profile papers. There is also a "Wang for Japan" who is a professor at Tokyo University. Several papers of this groups on RNAi are now in questions.

Jan Hendrik Schön: fired from Bell Labs after an inquiry found falsification of data.From the current situation, several journals are trying to implement new approaches to improve the peer-review quality. The fact that most of the reported misconducts are from high profile researchers in their high-profile papers does not mean that there is fewer misconducts in low profile papers. Instead, we should understand that, high-profile papers are being the leading directions for several researchers, and hence, get lots of attentions from them. Some will try to replicate it, while other based on the data of high-profile papers to design their own researchs.

So what is the driving force behind these misconducts? want to be farmous? try to get more grants? to keep a tenured track position? or just accidently? or else? I think the answers are complicated to say.

What is the effect of this scientific misleading? your comments and opinions are welcome! If you want to submit a view, just login and you will be able to post it.